Cancer research paper example. Cancer Essay Examples 2022-12-10
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Cancer is a disease that has plagued humanity for centuries, with instances dating back to ancient civilizations. It is a disease characterized by the uncontrolled growth and spread of abnormal cells in the body, which can lead to a range of serious health problems and even death. Despite significant progress in understanding and treating cancer over the years, it remains one of the leading causes of death worldwide. In this essay, we will provide an example of a cancer research paper to illustrate the current state of knowledge on this complex and multifaceted disease.
The paper, entitled "Exploring the Role of DNA Methylation in Breast Cancer Progression," was published in the Journal of the National Cancer Institute in 2015. The study was conducted by a team of researchers at the University of California, San Francisco and focused on the role of DNA methylation – a chemical modification of DNA that can affect gene expression – in breast cancer development and progression.
The researchers began by reviewing the existing literature on DNA methylation and its potential role in cancer. They found that DNA methylation is a key mechanism by which cells regulate gene expression and that abnormal methylation patterns have been observed in a number of different cancer types. However, the specific role of DNA methylation in breast cancer and its potential as a therapeutic target had not been well-studied.
To investigate this further, the researchers conducted a series of experiments using human breast cancer cells and animal models. They found that DNA methylation was significantly altered in breast cancer cells compared to normal cells and that these changes were associated with increased tumor growth and spread. They also identified specific genes that were differentially methylated in breast cancer cells and found that altering the methylation of these genes had a significant impact on cancer cell behavior.
Based on these findings, the researchers concluded that DNA methylation is an important contributor to breast cancer progression and that targeting DNA methylation may have therapeutic potential in the treatment of this disease. However, they also noted that further research is needed to fully understand the complex relationship between DNA methylation and breast cancer and to develop targeted therapies based on these findings.
Overall, this cancer research paper serves as a good example of the current state of knowledge on the role of DNA methylation in breast cancer and highlights the potential of this mechanism as a therapeutic target. While much work remains to be done in this field, these findings represent an important step towards improving our understanding of this complex disease and developing more effective treatments for those affected by cancer.
Research Paper on Cancer
ADVERTISEMENTS: Most striking feature of cancer cells is the alteration of chromosomes within the nucleus. Asian-Pacific Journal of Cancer Prevention 6 1 : 22—26. Probably 58% of the cases are concentrated in South and Southeast Asia Nair et al. In the United States, the Environmental Protection Agency EPA has enforced limits on concentrations of benzene in drinking water, with the ultimate aim being to abolish it altogether. How can we learn more with less testing? However, while much progress has been made in the treatment of childhood leukemia, this has not been matched in terms of delineating the underlying causes of the disease Lightfoot and Roman, 2004. Occupation Control of occupational carcinogens has been an important contributor to the recent reduction in bladder cancer mortality, particularly among males.
As a consequence, several patients go through the classic toxicities of alopecia, myelosuppression, and gastrointestinal signs. Presently, there are approximately 2. Although the establishment of a new standard nomenclature for incipient pancreatic cancer is an important first step, the participants in the histology working group agreed that additional studies are needed to validate the reproducibility of this classification system and, very importantly, to define the genetic alterations associated with each grade of PanIN as well as the risk of each lesion progressing to cancer. Smokeless tobacco ST products include paan or pan , chaalia, gutka, and naswar and are used in all sections of South Asian society. The risk of having breast cancer may be reduced if moderation is employed against this kind of risk. World Journal of Urology 21: 392—401. Significant advances in laboratory techniques over the last 100 years have underpinned progress in the classification of leukemia, which in turn has enabled the development of improved treatments.
Two important processes in carcinogenesis include apoptosis programmed cell death and hyperproliferation 43. Sometimes they may not occur other times they will. Most of the cells are pre-programmed to die after a certain number of cell divisions. Risk Factors Several epidemiological studies investigated in different populations the role of potential risk factors in bladder carcinogenesis, and a few etiological agents are now established. Journal of Epidemiology and Community Health 44: 286—292. Lyon, France: International Agency for Research on Cancer. Some of the drugs used in chemotherapy management of skin cancer management include 5-fluorouracil and imiquimod.
The incidence of breast cancer is still rising worldwide, although mortality rates are kept at bay by earlier diagnosis and the increasing number and efficacy of treatment options Schulz, 2005; Abdulkareem, 2013. A review of two cohort studies and 14 case—control studies showed a possible association between marijuana use and cancer risk Hashibe et al. Symptoms may comprise sputum streaked with blood, persistent cough, chest pain, recurrent pneumonia or bronchitis and voice change. Detection can be done through routine testing with the PSA test. As a consequence, the breach in mortality rates between disadvantaged and advantaged segments of the US populace has persisted to broaden. .
The size of the tumors also determine the survival rate in a patient. Research Paper Cancer and Cell Cycle: Factors that control the cell cycle can play a prominent role in the development of cancer. Chemotherapy is not usually used for patients with early stage of breast cancer. There are various causes for lung Cancer and the number of deaths in the world occurring due to this disease is increasing. Potential specimen sources include serum or plasma; pancreatic juice obtained via ERCP or secretin stimulation; or pancreatic cells obtained by fine-needle aspiration, cytological brushings, or large-bore-needle biopsy. Systemic Treatment of Breast Cancer Treatment Of Locally Advanced Disease The presence of estrogen and progesterone receptors in tumor cells shown by immunohistochemical staining is a good predictor of endocrine-responsiveness.
One of the treatment procedures developed recently for low-risk skin cancer tumors is cryosurgery, which focuses on freezing the surrounding margin of the tumor. Loss of cell division regulation due to mutations of proto-oncogenes and tumor suppressor genes cause uncontrolled cell division. In Europe, there were an estimated 370 000 new cases and 130 000 deaths in 2004. Tertiary prevention is a term that can be applied to the protection of individuals who have previously been treated for cancer from developing a second primary tumor Figures 2 and 3; Table 2. Cancer Research 54: 4103—4111. Overview Cancer of the breast develops in breast tissues.
OSCC incidence has also changed in Pakistan and India Gupta, 1999. Development of new treatments for CML has also been focused on the presence of the t 9;22 translocation: Chemical agents have been generated that block the tyrosine kinase activity of the abnormal BCR-ABL protein. It has an annual incidence of two to three cases per 100 000 per year and a male-to-female ratio of 2:1. Cancer prevention should be given a priority in the human heath since it is one the diseases that leading in causing of deaths. These mutations are known as gain-of-function mutations. Annals of Epidemiology 3 3 : 225—234. Conclusion Three types of skin cancer have been identified, melanoma, basal and squamous cell cancers.
The cancers diagnosed in women who have used combined oral contraceptives tend to be less advanced clinically than those diagnosed in women who have never used them. Rare symptoms comprise persistent changes to the breast, such as thickening, distortion, swelling, tenderness, redness, skin irritation and nipple abnormalities, such as retraction, ulceration, or spontaneous discharge. She was well aware of the importance of oxygenation, or the lack thereof, in cancer. With the development of technology in the last 2 decades of the 20th century, new applications were introduced. The review conducted by Kim et al. Radiotherapy For Ductal Carcinoma In Situ The role of radiotherapy in ductal carcinoma in situ DCIS managed with conservative treatment has been defined by results from three randomized trials.
Oral Oncology 33: 302—312. Mortality rates for leukemia are slightly higher in men 8. In G phase of cell cycle pRB protein binds to some transcription factors known as E2F family of transcription factors. Risk Factors There are various etiological or risk factors that affect the likelihood of a person to develop breast cancer. Some subgroups of patients may be expected to have a low risk of local recurrence, and radiotherapy could therefore be avoided.